Tumor Necrosis Factor : Structure, Enzyme Regulation & Role in Health & Disease Paperback / softback
Edited by Agueda Escarra
Tumor necrosis factor-alpha (TNF-a) is a potent pro-inflammatory cytokine exerting pleiotropic effects on various cell types and plays a critical role in the pathogenesis of chronic inflammatory diseases.
In this book, the authors discuss the structure, enzyme regulation and role in health and disease of TNF.
Topics include TNF-a related to signal pathways and neuronal diseases; the role of TNF-a in rheumatoid arthritis and autoimmunity; the presence of 308-A TNF allele and its association with the clinical parameters of myelodysplastic syndromes; the significance of TNF in the immune response against tuberculosis; and TNF-a signaling and cathespin B.
- Format: Paperback / softback
- Pages: 110 pages
- Publisher: Nova Science Publishers Inc
- Publication Date: 19/06/2013
- Category: Immunology
- ISBN: 9781624177217